Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 3034-38-6, name is 5-Nitro-1H-imidazole, A new synthetic method of this compound is introduced below., Application In Synthesis of 5-Nitro-1H-imidazole
Reference example 1 Preparation of 2,5-dibromo-4-nitroimidazole To a suspension of water (100 ml), 4-nitroimidazole (25 g) and sodium hydrogencarbonate (40.87 g), was dropwisely added bromine (26.5 ml) at lower than 10C, the reaction mixture was stirred at 25 to 30C for 1 hour, and at 50 to 60C for 4 hours. Then concentrated hydrochloric acid was added to the reaction mixture at lower than 10C to adjust pH 1, the crystals separated were collected by filtration, and were washed thoroughly with water. The crystals were dried at 50C under a reduced pressure for 24 hours, there was obtained 51.01 g (85.2%) of 2,5-dibromo-4-nitroimidazole of pale yellow powdery product.
The synthetic route of 3034-38-6 has been constantly updated, and we look forward to future research findings.