Reference of 109012-24-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 109012-24-0, name is 1-Methyl-4-nitro-1H-imidazole-2-carboxylic acid belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
EXAMPLE 2 Synthesis of N-(N’,N’-dimethylaminoethyl)-1-methyl-4-{4-[4,4-bis(2-chloroethyl)aminobenzamido]-1-methylimidazole-2-carboxamido}imidazole-2-carboxamide (Compound 6) To a suspension of 1-methyl-4-nitroimidazole-2-carboxylic acid (3.00 g, 17.5 mmol) in dry THF (30 mL) was slowly added oxalyl chloride (12 mL). The reaction mixture was heated to reflux under a drying tube for 45 minutes at which time the excess oxalyl chloride and THF were removed under reduced pressure and the acid chloride coevaporated twice with dry CH2 Cl2 (20 mL each) yielding 1-methyl-4-nitroimidazole-2-carbonyl chloride as a yellow powder.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Methyl-4-nitro-1H-imidazole-2-carboxylic acid, other downstream synthetic routes, hurry up and to see.