Synthetic Route of 17334-08-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 17334-08-6, name is (1-Methyl-1H-imidazol-2-yl)methanol, This compound has unique chemical properties. The synthetic route is as follows.
1-Methyl-2-hydroxymethyl imidazole (15.0 g, 134 mmol) was added, with shaking and exclusion of moisture, over a period of 15 min to ice cooled thionyl dichloride (24.6 mL, 30 g, 0.25 mol). The reactants were then heated under reflux for 15 min. The cooled solution was evaporated under reduced pressure followed by recrystallization from ethanol (25 mL) and dried under high vacuum to give 2-(chloromethy1)-1-methyl-1H-imidazole hydrochloride as brown crystals. Yield: 15.1g, 88%. 1H NMR (CDCl3) delta ppm: 7.79 (s, 1H), 7.70 (s, 1H), 5.2 (s, 2H), 3.86 (s, 3H). 3C NMR (CD3OD) delta ppm: 142.05, 124.7, 119.08, 33.9, 31.4. TOF-MS m/z: 131.0384 (M+H+, 100%). Molecular formula of cation, C5H7N2Cl, calculated m/z of cation: 131.04 (M+H+)
The chemical industry reduces the impact on the environment during synthesis (1-Methyl-1H-imidazol-2-yl)methanol. I believe this compound will play a more active role in future production and life.