Adding a certain compound to certain chemical reactions, such as: 28890-99-5, name is 5H-Benzo[d]benzo[4,5]imidazo[1,2-a]imidazole, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 28890-99-5, Quality Control of 5H-Benzo[d]benzo[4,5]imidazo[1,2-a]imidazole
9-fluorodibenzofuran-2-carbonitrile (1.6 g, 7.58 mmol), 6H-benzimidazolo[1 ,2-a]benzimidazole (1 .65 g, 7.96 mmol), and potassium phosphate (3.38 g, 15.91 mmol) are suspended in 39 mL of NMP, and the mixture is stirred at 185 C for 14 h. After the reaction mixture is cooled at room temperature, it is diluted with 76 mL of water and 38 mL of EtOH. The solid is collected by filtration, and dried in vacuum oven at 50 C. The crude product is purified by column chromatography on silica gel eluting with chloroform to yield 2.21 g (73%) of 9-(benzimidazolo[1 ,2- a]benzimidazol-5-yl)dibenzofuran-2-carbonitrileas a white solid. 1H-NMR (300 MHz, DMSO-afe): delta 8.36-8.26 (m, 2H), 8.08-7.83 (m, 5H), 7.61 -7.54 (m, 2H), 7.48 (td, .7 =1.1 , 7.8 Hz, 4H), 7.36-7.30 (m, 3H), 7.19 (d, J = 7.8 Hz, 1 H)
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.
Reference:
Patent; IDEMITSU KOSAN CO., LTD.; RAIMANN, Thomas; SCHAeFER, Thomas; SAITO, Masatoshi; WOLLEB, Heinz; BENEDITO, Flavio Luiz; NISHIMAE, Yuichi; NAKANO, Yuki; NAGASHIMA, Hideaki; (111 pag.)WO2016/157113; (2016); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem