Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 583-39-1, name is 2-Mercaptobenzimidazole, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 583-39-1
A mixture of benzimidazole-2-thione (7) (1.5 g, 10 mmol), triethylamine (2.88 g, 28.5 mmol), a catalytic amount (100 mg) of DMAP and anhydrous dichloromethane was stirred at room temperature for 10 min. A solution of acetyl chloride (2.83 g) and anhydrous dichloromethane was added dropwise and stirring was continued for 16 h. After diluting with water (100 ml) and dichloromethane (50 ml), the organic layer was separated, washed three times with an aqueous solution of potassium hydrogen sulfate (1 M, 50 ml) and water (50 ml) and dried over sodium sulfate. The solvent was removed under reduced pressure, and the product was purified by column chromatography on silica gel eluting with a 1:8 (v/v) mixture containing ethyl acetate and petroleum ether at 60-80 C to give a white solid. The product decomposes at ambient temperature and moisture to 1-acetylbenzimidazole-2-thione. Yield 1.3 g (5.55 mmol), 56%, white solid. Mp: 100-102 C (Mp: 102-103 C refPreviewPlaceHolder[40]). 1H NMR (CDCl3) delta 3.05 (s, 6H, OCH3), 7.31 (dd, 2H, 4J = 3.4 Hz, 3J = 6.3 Hz, H-5 and H-6), 7.97 (dd, 2H, 4J = 3.4 Hz, 3J = 6.3 Hz, H-4 and H-7). MS (EI) m/z 234 (M+). Anal. (C11H10N2O2S) C, H, N, S.
According to the analysis of related databases, 583-39-1, the application of this compound in the production field has become more and more popular.
Reference:
Article; Braun, Stephan; Botzki, Alexander; Salmen, Sunnhild; Textor, Christian; Bernhardt, Guenther; Dove, Stefan; Buschauer, Armin; European Journal of Medicinal Chemistry; vol. 46; 9; (2011); p. 4419 – 4429;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem