Synthetic Route of 939-70-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 939-70-8 name is 1-(1H-Benzo[d]imidazol-2-yl)ethanone, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
To a solution of 1-(1H-benzo [d] imidazol-2-yl)ethanone (2) (0.01 mol) in ethanol (60 ml),benzaldehyde (0.01 mol) and a few drops of glacialacetic acid were added and the mixture refluxed for10 hr. It was then cooled concentrated and pouredinto crushed ice and filtered. The solid thus obtainedwas purified by recrystallizaton from ethanol.1 H NMR (400 MHz, DMSO-d6): delta 6.81 (d, 1H,J=10.2 Hz), 6.98-7.20 (m, 5H), 7.24 (d, 1H, J=10.2Hz), 7.42 (m, 4H), 10.24 (brs, 1H). Mass [M+H], 249.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-(1H-Benzo[d]imidazol-2-yl)ethanone, and friends who are interested can also refer to it.
Reference:
Article; Bhaskar; Bharahmeswari; Indian Journal of Heterocyclic Chemistry; vol. 23; 2; (2013); p. 207 – 212;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem