In an article, author is Ogretir, C, once mentioned the application of 616-47-7, Recommanded Product: 616-47-7, Name is 1-Methyl-1H-imidazole, molecular formula is C4H6N2, molecular weight is 82.1, MDL number is MFCD00005292, category is imidazoles-derivatives. Now introduce a scientific discovery about this category.
Spectroscopic determination of acid dissociation constants of some imidazole derivatives
The acid dissociation constants, pK(a), of eight biologically active imidazole derivatives were determined using a spectroscopic technique. Using the obtained acid dissociation constants, attempts were made to elucidate the structures and protonation mechanisms of these derivatives. Four of eight molecules were found to behave as Hammett base for the first protonation.
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