Application of 1072-62-4, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 1072-62-4, Name is 2-Ethyl-1H-imidazole, SMILES is CCC1=NC=CN1, belongs to imidazoles-derivatives compound. In a article, author is Schiaffella, F, introduce new discover of the category.
Synthesis and antifungal activity of new imidazole derivatives of 1,4-benzothiazine
A new series of 1,4-benzothiazine imidazole derivatives, which differ with respect to N-4 substitution, the degree of S-1 and C-3 oxidation and azolic side chain insertion on the benzothiazine nucleus, was synthesized to clarify structure-activity relationships. The in vitro and in vivo evaluations against C. albicans showed that N-methyl derivatives were the most active derivatives, especially those linked at the C-6 position of 1,4-benzothiazine, with an appreciable antifungal activity for compound 5e and even more for its ether derivative 6e and sulfoxide 10e. Derivative 10a, the sulfoxide of previously synthesized compound la, also showed good activity.
Application of 1072-62-4, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 1072-62-4.