Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 10045-45-1, Name is 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one, molecular formula is , belongs to imidazoles-derivatives compound. In a document, author is Jayabharathi, Jayaraman, Application In Synthesis of 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one.
Antioxidant potential and antimicrobial screening of some novel imidazole derivatives: greenway efficient one pot synthesis
A series of substituted imidazoles have been synthesized under solvent-free condition by grinding 1,2-diketone, aromatic aldehyde, and ammonium acetate in the presence of molecular iodine as the catalyst. The short reaction time and easy workup make this protocol practically and economically attractive and are characterized by NMR spectra, X-ray, mass, and CHN analysis. Their antioxidant potential were evaluated using different in vitro antioxidant models namely, DPPH (1,1-diphenyl-2-picrylhydrazyl) radical, superoxide anion, and hydroxyl radical scavenging activities. Their antibacterial screening against Staphylococcus aureus, Escherichia coli, and Klbesiella pneumoniae and antifungal activity against Aspergillus niger, Aspergillus flavus, and Candida-6 were also evaluated. Among all, dimethoxyphenyl substituent at N3 of the imidazole derivatives exhibited the highest hydroxy and superoxide anion radical scavenging activities, whereas dimethoxyphenyl substituent at N3 and fluorophenyl at C2 of the imidazole derivatives exhibited the highest DPPH radical scavenging activity.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 10045-45-1, in my other articles. Application In Synthesis of 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one.