Chemistry is an experimental science, Application In Synthesis of 1H-Benzo[d]imidazol-2-amine, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 934-32-7, Name is 1H-Benzo[d]imidazol-2-amine, molecular formula is C7H7N3, belongs to imidazoles-derivatives compound. In a document, author is Smitha, M..
Two novel imidazole derivatives – Combined experimental and computational study
Two novel imidazole derivatives, 2-chloro-4,5-dimethyl-1-phenyl-1H-imidazole (C11H11ClN2)(PHENYLI) and 2-chloro-4,5-dimethyl-1-(o-tolyl)-1H-imidazole (C12H13ClN2) (TOLYLI), have been obtained by a procedure based on solvent-free synthesis pathway. Newly synthetized imidazole derivatives have been characterized experimentally by IR, FT-Raman and NMR techniques, while their reactive properties have been predicted on the basis of density functional theory (DFT) calculations and molecular dynamics (MD) simulations. The NLO behavior of the title compounds is greater than that of the standard NLO material urea. MEP analysis gives the most reactive sites in the molecules. TOLYLI compound reveals anti-bacterial activity against all four bacterial strain in both gram positive and gram negative bacteria and PHENYL! compound showed in gram positive and gram negative bacteria both with very good immense and has more sensitive. Interactions of these novel imidazole derivatives with selected protein have been computationally investigated by molecular docking procedure. The docking studies suggest that the compounds might exhibit inhibitory activity against APO-liver alcohol dehydrogenase inhibitor. (C) 2018 Elsevier B.V. All rights reserved.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 934-32-7. Application In Synthesis of 1H-Benzo[d]imidazol-2-amine.