Chemistry, like all the natural sciences, Recommanded Product: 144689-94-1, begins with the direct observation of nature¡ª in this case, of matter.144689-94-1, Name is Diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate, SMILES is O=C(C1=C(C(OCC)=O)NC(CCC)=N1)OCC, belongs to imidazoles-derivatives compound. In a document, author is Panigrahi, Ahwan, introduce the new discover.
Iodine-Catalyzed C-H Functionalization of Cyclopentenedione with Benzamidine: A Double Dehydrogenative Oxidative Cyclization to Access Fused Imidazoles
A double C-H functionalization of cyclopentenedione with benzamidine hydrochloride catalyzed by iodine has been disclosed for synthesizing fused imidazole derivatives. This methodology leads to a variety of fused imidazole derivatives and requires a sub-stoichiometric amount of iodine as a catalyst and aqueous tert-butyl hydroperoxide (TBHP) as an oxidant. This reaction involves a double-cross dehydrogenative coupling (CDC) of 1,3-cyclopentenedione and benzamidine hydrochloride to form two C-N bonds in a consecutive manner within short reaction time. A plausible mechanism has been proposed based on the mass spectrometric analysis.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 144689-94-1. Recommanded Product: 144689-94-1.