Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 16079-88-2, Name is 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione, molecular formula is C5H6BrClN2O2, belongs to imidazoles-derivatives compound. In a document, author is Birsan, Magdalena, introduce the new discover, Recommanded Product: 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione.
Antifugal Action of Imidazole Derivatives from New Pharmaceutical Forms on Various Strains of Candida
The antifungal activity of imidazole derivatives was tested on three types of Candida, respectively C. albicans, C. sake, and C. glabrata. The antifungal activity was compared with the activity of miconazole nitrate in 16 new formulations of oral biomucoadhesive tablets, with the purpose of being used in oral candidiasis. All the 16 formulations of biomucoadhesive tablets which contain 25 mg miconazole have a good antifungal action; the diameter of the inhibition area is over 20 mm in all the three strains of Candida. The second goal was to compare the activity of miconazole nitrate with other antifungal substances: clotrimazole (benzyl imidazole derivative), nistatin (polyenic macrolide), econazole (phenyl – ethyl – imidazole derivative), and fluconazole (triazole derivative). Good results, obtained by measuring the diameter of the inhibition area, were shown by econazole, with a diameter of over 22 mm, but this imidazole derivative does not penetrate the stratum corneum well enough, which implies a much longer treatment than miconazole. The third goal was the assessment of the antifungal activity of the 16 formulations of biomucoadhesive tablets by means of establishing the minimum inhibitory concentration (MIC) and of minimum fungicide concentration (MFC).
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 16079-88-2. Recommanded Product: 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione.