Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.16079-88-2, Name is 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione, SMILES is O=C1N(Cl)C(C(C)(C)N1Br)=O, belongs to imidazoles-derivatives compound. In a document, author is Kim, Dae-Kee, introduce the new discover, Quality Control of 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione.
Synthesis and biological evaluation of trisubstituted imidazole derivatives as inhibitors of p38 alpha mitogen-activated protein kinase
A series of trisubstituted imidazole derivatives containing a 4-fluorophenyl group, a pyrimidine ring, and a CN- or CONH(2)-substituted benzyl moiety have been synthesized and evaluated for p38 alpha MAP kinase inhibitory activity. Among them, compounds 22c, 27b, and 28b inhibited p38 alpha MAP kinase with IC(50) values 27.6, 28, and 31 nM, respectively. (c) 2008 Elsevier Ltd. All rights reserved.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 16079-88-2 is helpful to your research. Quality Control of 1-Bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione.