Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.38668-46-1, Name is 6-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-1,3,5-triazine-2,4-diamine, SMILES is CC1=NC=CN1CCC2=NC(N)=NC(N)=N2, belongs to imidazoles-derivatives compound. In a document, author is Morin, N, introduce the new discover, Recommanded Product: 6-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-1,3,5-triazine-2,4-diamine.
HPLC retention and inclusion of imidazole derivatives using hydroxypropyl-beta-cyclodextrin as a mobile phase additive
Using the results of high performance liquid chromatography (HPLC), this paper investigates the separation and inclusion of a series of weakly polar imidazole derivatives, with hydroxypropyl-beta-cyclodextrin (HP-beta-CD) in the mobile phase over a wide range of column temperatures. These compounds are used for the treatment of onychomycosis. Gibbs Helmholtz parameters (Delta(Delta H) and Delta(Delta S)) of two adjacent imidazole peak on a chromatogram were determined from the graph of the logarithm of the separation factor, alpha, against the reciprocal of the temperature. A temperature dependent reversal of the elution order between a pair of imidazole derivatives was studied. The results revealed that the main parameter determining interactions between imidazole derivatives and HP-beta-CD increased as follows: HP-beta-CD double left right arrow solute hydrogen bonding interaction > HP-beta-CD double left right arrow solute complexation.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 38668-46-1 is helpful to your research. Recommanded Product: 6-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-1,3,5-triazine-2,4-diamine.