Electric Literature of 1072-63-5, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 1072-63-5, Name is 1-Vinyl-1H-imidazole, SMILES is C=CN1C=CN=C1, belongs to imidazoles-derivatives compound. In a article, author is EL-Sharief, Marwa A. M. Sh, introduce new discover of the category.
Synthesis and Evaluation of Antibacterial and Antifungal Activities of 1,3-Disubstituted-4-thioxoimidazolidin-2-one Derivatives
1,3-Disubstituted-4-thioxoimidazolidin-2-one derivatives with various substituents at N(1 )and N-3 were synthesized with high yields and excellent purity by the reaction of various N-arylcyanothioformamide derivatives with isocyanate derivatives. The activity of these products as antibacterial and antifungal agents was studied to through some light on structural activity relationship. Some of synthesized compounds showed significant antibacterial and antifungal activities. Most of the imidazole derivatives possess significant antifungal activity aginst S. cerevisiae (MIC 1-10 mu g mL(-1)). As comparision with ketoconazole, most of the imidazole derivatives showed activity ranging from 50 % less activity to fourfold activity.
Electric Literature of 1072-63-5, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 1072-63-5 is helpful to your research.