Related Products of 45676-04-8,Some common heterocyclic compound, 45676-04-8, name is 1-tert-Butylimidazole, molecular formula is C7H12N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
E) 1,1′-Di-tert-butyl-3,3′-methylenedimidazolium dibromide 12 0.008 mol of dibromomethane (1.391 g; 0.56 ml) and 5 ml of tetrahydrofuran are added to 0.016 mol of tertbutylimidazole 2 (2.000 g) in an ACE pressure tube. The reaction mixture is stirred at 80 C. for 20 hours. The solid which precipitates is washed repeatedly with a little tetrahydrofuran. A white solid 12 is obtained. Empirical formula: C15H26N4Br2 M=422.206 g/mol Yield: 1.449 g (42.9% of theory) Melting point: decomposition at >230 C. 1H (ppm, d6-DMSO, 300.13 MHz): delta=9.85 (s, 2H, NCN); 8.21 (s, 2H, NCCHN); 8.17 (s, 2H, NCHCN); 6.67 (s, 2H, NC2N); 1.62 (s, 18H, C3 group)
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1-tert-Butylimidazole, its application will become more common.
Reference:
Patent; BASF SE; TECHNISCHE UNIVERSITAET DRESDEN; US2009/326237; (2009); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem