Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 36947-68-9, name is 2-Isopropyl-1H-imidazole, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 2-Isopropyl-1H-imidazole
43-a : Synthesis of 1-(4-chloro-2-nitrophenyl)-2-isopropyl-1H-imidazole A mixture of 1.01 g of 4-chloro-1-fluoro-2-nitrobenzene, 634 mg of 2-isopropylimidazole, 1.46 mL of N,N-diisopropylethylamine and 12 mL of acetonitrile was heated under reflux for 15 hours. The solvent was distilled off, water was added, and the reaction liquid was rendered acidic with diluted hydrochloric acid, followed by washing with diethyl ether. The aqueous layer was rendered alkaline with aqueous sodium hydroxide solution, and extracted twice with chloroform. The organic layer was washed with water, dried over magnesium sulfate, and removed of the solvent by distillation to provide 0.98 g of the title compound. 1H-NMR(CDCls,delta):1.22(6H,d,J=6.9Hz),2.5-2.8(1H,m), 6.81(1H,d,J=1.2Hz),7.09(1H,d,J=1.5Hz),7.39(1H,d,J=8.5Hz), 7.71(1H,dd,J=2.3,8.5Hz),8.05(1H,d,J=2.7Hz) MS(m/z):267(M++2), 265(M+)
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 36947-68-9.
Reference:
Patent; ASKA Pharmaceutical Co., Ltd.; EP2123301; (2009); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem