Adding a certain compound to certain chemical reactions, such as: 104619-51-4, name is Di(1H-imidazol-1-yl)methanimine, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 104619-51-4, Quality Control of Di(1H-imidazol-1-yl)methanimine
Example 48: r4-(5-Amino- M.3,41 oxadiazot-2-yl>-5-fluoro-pyridin-3-v?-(2-fluoro-4- iodo-phenvD-amine; To a solution of 3-Fluoro-5- (2-fluoro-4-iodo-phenylamino)-isonicotinic acid hydrazide (100mg0.26mmol, 1eq) in DMSO (2mL) C- (Di-imidazol-i-yl)-methyleneamine (123mg, 0.77mmol, 3eq) was added. The reaction mixture was stirred at RT under argon overnight and then poured- into water. A solid precipitated out that was filtered out and washed with methanol to afford the desired product (65 mg). LC/MS (Method A) [5.19min; 416(M-H)]
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Di(1H-imidazol-1-yl)methanimine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.; WO2007/123936; (2007); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem