Adding a certain compound to certain chemical reactions, such as: 28890-99-5, name is 5H-Benzo[d]benzo[4,5]imidazo[1,2-a]imidazole, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 28890-99-5, Recommanded Product: 5H-Benzo[d]benzo[4,5]imidazo[1,2-a]imidazole
2.5 g (15.9 mmol) 2,3,4-trifluorobenzonitrile, 10.9 g (52.5 mmol) 6H-benzimidazolo[1 ,2- a]benzimidazole and 27.0 g (0.127 mol) potassium phosphate tribasic in 50 ml NMP (N-Methyl- 2-pyrrolidon) are stirred at 1 15 C under nitrogen for 18 h. The reaction mixture is filtered hot and the organic phase is poured on water. The product is filtered of. Column chromatography on silica gel with chloroform gives 1 .3 g (1 1.4 %) of the product. 1H NMR (300 MHz, DMSO-D6): rotamers: delta 8.55-8.82 (m, 2H); 6.41 -8.07 (m, 24H) MS (APCI(pos), m/z): 719 (M+1).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 5H-Benzo[d]benzo[4,5]imidazo[1,2-a]imidazole, and friends who are interested can also refer to it.
Reference:
Patent; IDEMITSU KOSAN CO., LTD.; RAIMANN, Thomas; SCHAeFER, Thomas; SAITO, Masatoshi; WOLLEB, Heinz; BENEDITO, Flavio Luiz; NISHIMAE, Yuichi; NAKANO, Yuki; NAGASHIMA, Hideaki; (111 pag.)WO2016/157113; (2016); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem