Synthetic Route of 33543-78-1, These common heterocyclic compound, 33543-78-1, name is Ethyl 1H-imidazole-2-carboxylate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Reference example 1 2-hydrazinocarbonylimidazole 2-ethoxycarbonylimidazole was prepared according to the method given in the literature, J. Org. Chem., Vol.43, No.22, 4381 Kenneth L. kirk. 80percent hydrazine hydrate (4.6g, 75mmol) was added dropwise to a solution of 2-ethoxycarbonylimidazole (2.1g, 15mmol) in ethanol (20ml) at room temperature and stirring was continued for 2 h. The precipitate was filtered, washed with water and dried to give the title compound (1.7g, 90.0percent).
Statistics shows that Ethyl 1H-imidazole-2-carboxylate is playing an increasingly important role. we look forward to future research findings about 33543-78-1.
Reference:
Patent; Wakamoto Pharmaceutical Co., Ltd.; EP713876; (1996); A1;,
Imidazole – Wikipedia,
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