Adding a certain compound to certain chemical reactions, such as: 53316-51-1, name is 4,5-Dimethyl-1H-imidazole hydrochloride, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 53316-51-1, COA of Formula: C5H9ClN2
A solution of 4,5-dimethylimidazolium hydrochloride (82) (8.00 g, 60.3 mmol) in anhydrousDMSO (100 mL) was treated with solid 90% KOH (11.20 g, 180 mmol) and bromoethane (4.9 mL, 65mmol). The obtained mixture was stirred under argon and heated at 40C for 16 hours. The reaction mixture was poured into ice-water (500 mL), treated with SN NaOH and extracted with DCM/THF (9:1, 2 x 200 mL). The extract was washed with water (100 mL), dried over Na2CO3, and the solvent was removed under reduced pressure to give 1-ethyl-4,S-dimethylimidazole (87-0) (5.43 g, 73% yield).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4,5-Dimethyl-1H-imidazole hydrochloride, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; NITTO DENKO CORPORATION; STANISLAW, Rachwal; HU, Yufen; ZHANG, Hongxi; (0 pag.)WO2018/161025; (2018); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem