Application of 288-32-4, These common heterocyclic compound, 288-32-4, name is 1H-Imidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: Imidazole was chosen as the model substrate for theN-arylation reaction in presence of electrospun CuO NFsas catalyst. The reaction flask was packed with 0.1 mM ofCuO NFs, 5 ml of DMF followed by the charging of imidazole(1 mM) and bromobenzene (1 mM) at 110 C withconstant stirring. The progress of the reaction was monitoredby thin layer chromatography (TLC). After completion,the catalyst was separated by centrifuge and washedseveral times with water and ethyl acetate for re-use. Theproduct was isolated by evaporation of solvent in vacuumand purified. The obtained product was characterized withFT-IR for functional group identification and GC-MS for structural confirmation.
Statistics shows that 1H-Imidazole is playing an increasingly important role. we look forward to future research findings about 288-32-4.
Reference:
Article; Sukumar, Thenmozhi; Nallasamy, Dharmaraj; Journal of Nanoscience and Nanotechnology; vol. 18; 1; (2018); p. 234 – 241;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem