Reference of 288-32-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 288-32-4, name is 1H-Imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
Under nitrogen, imidazole was dissolved in anhydrous THF, and an appropriate amount of acetic anhydride was dropped slowly into the solution; then reaction was carried out for about half an hour accompanied by exothermic phenomena. After the reaction was completed, the solvent was removed by vacuum reduced pressure concentration to generate a solid product. Then, the obtained solid was rinsed with n-hexane and filtered to provide compound 11 as white solid, with yield of about 98percent.
The synthetic route of 1H-Imidazole has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Eternal Chemical Co., Ltd.; Cheng, Pi-Jen; Chou, Meng-Yen; Lee, Chuan Zong; Wu, Chung-Jen; US2013/172569; (2013); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem