Adding a certain compound to certain chemical reactions, such as: 693-98-1, name is 2-Methyl-1H-imidazole, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 693-98-1, Quality Control of 2-Methyl-1H-imidazole
10 mmol of 2-methyl-1H-imidazole was added to a suspensionof potassium carbonate (10 mmol) in acetonitrile (10 mL), and then stirred for 15 min at r.t. 10 mmol of1-(chloromethyl)benzene was added to the reaction mixture and the mixture was heated to 70C and kept for 72 h. After completion of the reaction, the solvent was removed and the residue was dissolved in EtOAc (20 mL), washed with H2O(2¡Á10 mL) and concentrated under reduced pressure. The residue was purified by silica gel chromatography (eluent: CHCl3)to afford the desired product. Yield 38%; yellow oil; UV-Vis (chloroform, lambda, nm): 290; IR spectrum (KBr, nu, cm-1): 2939,1712, 1508, 1434, 1365, 1272, 1118, 983, 721; 1H NMR (250.13 MHz, CDCl3) delta: 7.43-7.32 (m, 5H), 7.17-7.14 (m, 2H), 6.99(d, J = 1.3 Hz, 1H), 6.84 (d, J = 1.2 Hz, 1H), 5.11 (s, 2H), 2.27 (s, 3H); 13C NMR (62.9 MHz, CDCl3) delta: 144.3, 138.0, 129.3,128.1, 127.5, 127.1, 120.9, 49.2, 13.4.
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Reference:
Article; Bouchouit; Bouraiou; Bouacida; Belfaitah; Merazig; Journal of Structural Chemistry; vol. 57; 4; (2016); p. 835 – 839; Zh. Strukt. Kim.; vol. 57; 4; (2016); p. 873 – 876,4;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem