Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 934-32-7, name is 1H-Benzo[d]imidazol-2-amine, A new synthetic method of this compound is introduced below., Application In Synthesis of 1H-Benzo[d]imidazol-2-amine
General procedure: A mixture of aromatic aldehyde 1 (1.0 mmol), dimedone 2 (1.0 mmol), 2-aminobenzimidazole 3 (1.0 mmol) and [DABCO](HSO3)2(Cl)2 (0.2 mmol, method A) or [DABCO](SO3H)2(HSO4)2 (0.02 mmol, method B) was stirred at 100 C for the appropriate time. The progress of the reaction was followed by TLC (n-hexane/ethyl acetate-8:2). After completion, the obtained solid mixture was washed with cooled water (2 ¡Á 2 mL) to separate the catalyst. Then, warm ethanol (3 mL) was added to the reaction media, and the solid product was filtered and dried in air.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Seyyedi, Narges; Shirini, Farhad; Langarudi, Mohaddeseh Safarpoor Nikoo; Jashnani, Setareh; Journal of the Iranian Chemical Society; vol. 14; 9; (2017); p. 1859 – 1867;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem