Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 33529-02-1, name is 1-Decyl-1H-imidazole, A new synthetic method of this compound is introduced below., Safety of 1-Decyl-1H-imidazole
Equipped with a stirrer, a thermometer, a three-necked flask was added 1.67 g (8.0 mmol) N- decyl-imidazole, 0.56 g (4.4 mmol) 1,3- dichloro-2-propanol, at 115 ~ 125 C The reaction was stirred after, TLC tracking progress of the reaction, the reaction of about 8 ~ 12 h, the crude product was mixed with chloroform and ethyl acetate solvent was recrystallized to give a white powdery solid 1,1′-didecyl-3,3 ‘- (2- hydroxy-1,3-propylene) imidazole hydrochloride 1.42 g, yield 65.2%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Qiqihar university; Wang, LiYan; Deng, QiGang; Zheng, YongJie; Huo, shichao; Liu, Jia; Sun, zhu; (10 pag.)CN103951702; (2016); B;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem