Synthetic Route of 934-32-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 934-32-7 name is 1H-Benzo[d]imidazol-2-amine, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: In a typical experiment, different aromatic aldehyde (1 mmol),1,3-cyclic diketon (1 mmol), 2-amino-benzimidazole (1 mmol) andcatalyst (0.019 g) in solvent free condition were taken in a 25 mLround bottomed flask. The flask was stirred at 100C for an appro-priate time. The reaction mixture was cooled, eluted with hotethanol (5 mL), centrifuged and filtrated to collect the formed pre-cipitate. The crude product was recrystallized from ethanol to yieldpure benzimidazoloquinazolinone derivatives.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1H-Benzo[d]imidazol-2-amine, and friends who are interested can also refer to it.
Reference:
Article; Amoozadeh, Ali; Rahmani, Salman; Journal of Molecular Catalysis A: Chemical; vol. 396; (2015); p. 96 – 107;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem