71759-89-2, name is 5-Iodo-1H-imidazole, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. category: imidazoles-derivatives
A mixture of 4-iodoimidazole (2.5 g, 12.89 mmol), CS2CO3 (6.3 g, 19.33 mmol) and BnBr (2.6 g, 15.47 mmol) in CH3CN (50 mL) was stirred at 80 C for 12 hrs. After being cooled to rt, the solid was filtered and the filtrate was concentrated in vacuo. The residue was purified by prep-HPLC to give l-benzyl-4-iodo-imidazole (2.68 g) as a white solid.
The synthetic route of 71759-89-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; CHENG, Zhanling; HAN, Xingchun; WANG, Yongguang; YANG, Song; (84 pag.)WO2018/83081; (2018); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem