Electric Literature of 39861-21-7, These common heterocyclic compound, 39861-21-7, name is 4-(5-Chloro-1H-benzo[d]imidazol-2-yl)aniline, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
(c) N-[4-(5-Chloro-1H-benzoimidazol-2-yl)-phenyl]-2-cyclohexylmethyl-succinamic acid methyl Ester This compound was prepared by the procedure described in Example 1 part (a) from 4-(5-Chloro-1H-benzoimidazol-2-yl)-phenylamine and (R)-2-(Cyclohexylmethyl) succinic acid 1-methyl ester to give the crude product (2.0 g, 51%), which was used in the next step without further purification.
The synthetic route of 39861-21-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Bekkali, Younes; Betageri, Rajashehar; Emmanuel, Michel Jose; Hickey, Eugene Richard; Liu, Weimin; Patel, Usha R.; Spero, Denice Mary; Thomson, David S.; Ward, Yancey David; Young, Erick Richard Roush; US2001/41700; (2001); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem