Related Products of 3287-79-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3287-79-4, name is 5,6-Dimethyl-1H-benzo[d]imidazole-2(3H)-thione belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
A mixture of 5,6-dimethyl-2-mercaptobenzimidazole (9.45 g, 0.053 mole), 1,8-diazabicyclo [5.4.0] undec-7-ene (9.7 g, 0.064 mole) and 1-iodo-2,2,2-trifluroethane (13.4 g, 0 064 mole) in 210 ml dimethylformamide is heated (50 C. for 41/2 hours), poured onto ice and water (1500 ml), and the precipated solid collected by filtration and dried. The product is recrystallized from toluene-ligroine giving 5,6-dimethyl-2-(2,2,2-trifluoroethyl-mercapto)-1H-benzimidazole (3.4 g, 0.013 mole), m.p. 150-163 C.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5,6-Dimethyl-1H-benzo[d]imidazole-2(3H)-thione, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Boehringer Ingelheim Pharmaceuticals, Inc.; US4608381; (1986); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem