Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 50995-95-4, name is 2-Propylimidazole, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 2-Propylimidazole
A stirred mixture of [5- (3-FLUORO-4-METHANESULFONYL-PHENYL)-4-METHYL-THIAZOL-2-YL]- (LH-PYRAZOL-3-YL)-AMINE hydrobromide salt (68d) (1.0 g, 2.3 mmol), Caesium carbonate (1.50 g, 4.6 mmol) and 2-propylamidazole (0. 508 g, 4.6 mmol) in dry DMSO (10 ml) is heated at 140 C for 6 hours. After cooling to room temperature the mixture is diluted with ethyl acetate (50 ml) and washed with water (100 ml). The organic extract is separated and the crude product is absorbed on silica. Purification by chromatography on silica, eluting with ethyl acetate-ethanol (1: 1) affords the titled compound.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 50995-95-4.
Reference:
Patent; NOVARTIS AG; NOVARTIS PHARMA GMBH; WO2004/78754; (2004); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem