Synthetic Route of 50995-95-4,Some common heterocyclic compound, 50995-95-4, name is 2-Propylimidazole, molecular formula is C6H10N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
1(a) Ethyl-2-(2-propylimidazol-1-yl)propanoate 2-Propylimidazole (5.5 g), ethyl 2-bromopropionate (9.95 g) and potassium carbonate (12.4 g) were stirred in refluxing acetonitrile (100 ml) for 72 hours. The suspension was allowed to cool, filtered and the solvent removed under reduced pressure, yielding the title compound as an off-white foam, 9.2 g [88%].
The synthetic route of 50995-95-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Pfizer Inc.; US4853392; (1989); A;; ; Patent; Pfizer Limited; EP299727; (1991); B1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem