Some common heterocyclic compound, 4238-71-5, name is 1-Benzyl-1H-imidazole, molecular formula is C10H10N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Computed Properties of C10H10N2
1 mol of the compound III obtained in the step (1)1 mol of benzyl chloride was dissolved in THF (tetrahydrofuran)Heated to reflux 12h,The above solution was spin-dry with a rotary evaporator,Then using 3: 1 CH 2 Cl 2 and CH 3 OH as the eluent for chromatographic separation,Obtained pale yellow oily liquid, which is Compound II;
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 4238-71-5, its application will become more common.
Reference:
Patent; Jiangsu Atomic Medical Institute; Lin Jianguo; Lv Gaochao; Qiu Ling; Guo Liubin; Yang Hui; Wang Tengfei; (17 pag.)CN104650155; (2017); B;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem