Adding a certain compound to certain chemical reactions, such as: 570-22-9, name is 1H-Imidazole-4,5-dicarboxylic acid, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 570-22-9, name: 1H-Imidazole-4,5-dicarboxylic acid
Thionyl chloride (94 ml; 1.29 mol) was added to a suspension of 1H-imidazole4;5- dicarboxylic acid (25 g; 157 mmol) in toluene (334 ml) and N;N-dimethylformamide (12.1 ml) and the mixture was stirred for 24 h at 80C. The mixture was concentrated under reduced pressure; 100 ml toluene were added and the mixture was concentrated under reduced pressure to give 35.5 g of the title compound as crude material; which was usedat the same day without further purification for subsequent steps.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1H-Imidazole-4,5-dicarboxylic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; EIS, Knut; ACKERSTAFF, Jens; WAGNER, Sarah; BUCHGRABER, Philipp; SUeLZLE, Detlev; BENDER, Eckhard; LI, Volkhart Min-Jian; LIU, Ningshu; SIEGEL, Franziska; LIENAU, Philip; (136 pag.)WO2017/55313; (2017); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem