Reference of 5805-57-2, A common heterocyclic compound, 5805-57-2, name is (1H-Benzo[d]imidazol-2-yl)methanamine, molecular formula is C8H9N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: NH4SCN (0.092 g, 1.2 mmol) was dissolved in water (5 ml) and slowly added to the methanolic solution of CuCl2¡¤2H2O (0.1 g; 0.59 mmol) and suitable N-donor ligand, and stirred at room temperature for 12 h. Green crystalline precipitates were filtered off and dried in air. The crystals suitable for X-ray structure determination were obtained by slow recrystallization from methanol.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Machura; ?witlicka; Mrozi?ski; Kali?ska; Kruszynski; Polyhedron; vol. 52; (2013); p. 1276 – 1286;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem