Synthetic Route of 68282-53-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 68282-53-1, name is 5-Methyl-1H-imidazole-4-carbaldehyde belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
EXAMPLE 8 SYNTHESIS OF 4-(3-CHLORO-4-FLUORO-PHENYLAMINO)-5-(5-METHYL-3H-IMIDAZOL4-YLMETHYLENE)-5,7-DIHYDRO-PYRROLO [2,3-D]PYRIMIDIN-6-ONE (FORMULA 8) 4-Chloro-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one (1 eq.) was condensed with 5-methyl-3H-imidazole-4-carbaldehyde (1 eq.) at room temperature to give (76.9%) of 4-chloro-5-(5-methyl-3H-imidazol-4-ylmethylene)-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one.
The synthetic route of 5-Methyl-1H-imidazole-4-carbaldehyde has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Liang, Congxin; Sun, Li; Wei, Chung Chen; Tang, Peng Cho; McMahon, Gerald; Hirth, Klaus Peter; Cui, Jingrong; US2002/183319; (2002); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem