Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 14741-71-0, name is Ethyl 2-(1H-benzo[d]imidazol-2-yl)acetate, A new synthetic method of this compound is introduced below., Recommanded Product: Ethyl 2-(1H-benzo[d]imidazol-2-yl)acetate
Example 45: Synthesis of 4-(4-Methyl-[l,4]diazepan-l-yl)-l,7,llb-triaza-benzo[c]fluorene- 6-carboxylic acid ethyl ester (Compound 8A) [0329] To a solution of SMI (176 mg, 1 mmol) and SM2 (204 mg, 1 mmol) in 2- Methoxyethanol (10 mL) was added N-Methylhomopiperazine (342 mg, 3 mmol) and the mixture was stirred at room temperature for 20 min. The reaction mixture was heated to reflux for 16h. The crude product was purification by gel silica column (DCM/MeOH=50: l) to get compound 8A as brown oil (320 mg, 79 yield). LCMS: m/z 404 (M+H)+.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; HADDACH, Mustapha; WO2015/172123; (2015); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem