Related Products of 288-32-4, These common heterocyclic compound, 288-32-4, name is 1H-Imidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
0.680 g (10 mmol) of imidazole was weighed and 1.240 g (10 mmol) of p-fluorobenzaldehyde and 1.380 g (10 mmol) of anhydrous potassium carbonate were weighed and dissolved in 25 mL of N, N-dimethylformamide, Thermometer, stirring device 50mL four-necked flask.60 C for 20h, cooled to room temperature, poured into 100mL ice water, a yellow solid precipitated, suction filtered, recrystallized from ethanol, dried at 50 C for 8h under vacuum to give 4-imidazolyl benzaldehyde
The synthetic route of 288-32-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Qilu University of Technology; Xu Ting; Duan Hongdong; Bu Juan; (12 pag.)CN107043353; (2017); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem