These common heterocyclic compound, 29914-81-6, name is 1,3-Bis(1H-benzo[d]imidazol-2-yl)benzene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. SDS of cas: 29914-81-6
1,3-bis(1H-benzo[d]imidazol-2-yl)benzene (MBImB) was first synthesized according to our earlier report [19]. 10.01 g MBImB was dissolved in anhydrous DMF, and then 3.5 g NaH encapsulated in mineraloil (60%) was added and stirred for 0.5 h. When the NaH reaction was completed, 1-bromopropane (9.0 g) was added. After degassing, the solution was heated at 100 C overnight under nitrogen atmosphere.After cooling, 200 ml water was added, and the aqueous layer was washed with CH2Cl2 (2¡Á30 ml). The combined organic extract was dried over Na2SO4, filtered, and concentrated under high vacuum. The pure product was obtained as a red viscous liquid. Yield, 71%. 1H NMR(300 MHz, CDCl3) delta 8.02 (s, 1 H), 7.90-7.78 (m, 4 H), 7.72-7.65 (m,1 H), 7.44 (dd, J=9.1, 5.1 Hz, 2 H), 7.39-7.29 (m, 4 H), 4.30-4.20(m, 4 H), 1.91-1.77 (m, 4 H), 0.85 (t, J =7.4 Hz, 6 H). ESI-MS m/z:394.1.
The synthetic route of 1,3-Bis(1H-benzo[d]imidazol-2-yl)benzene has been constantly updated, and we look forward to future research findings.
Reference:
Article; Li, Chao-Jie; Yin, Shao-Yun; Wang, Hai-Ping; Wei, Zhang-Wen; Pan, Mei; Journal of Photochemistry and Photobiology A: Chemistry; vol. 379; (2019); p. 99 – 104;,
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