256519-10-5, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 256519-10-5 name is 4-Fluoro-1H-benzo[d]imidazol-2(3H)-one, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Preparation 47 2-Chloro 4-fluoro-1H-1,3-benzimidazole STR92 The title compound was prepared by the method of Preparation 25 from 4-fluoro-1,3-dihydro-2H-1,3-benzimidazole-2-one [see Preparation 46]. 1 H-NMR (d4-MeOH) delta: 7.32 (1H, d), 7.28 (1H, m), 7.00 (1H, t).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4-Fluoro-1H-benzo[d]imidazol-2(3H)-one, and friends who are interested can also refer to it.
Reference:
Patent; Pfizer Inc; US6166011; (2000); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem