124750-59-0, Name is 2-Propyl-1H-imidazole-4,5-dicarboxylic acid dimethyl ester, 124750-59-0, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows.
Part B: Preparation of 1-[(2′-Carbomethoxybiphenyl-4-yl)methyl]-4,5-dicarbomethoxy-2-n-propylimidazole 2-n-Propyl-4,5-dicarbomethoxyimidazole (2.00 g, 8.8 mmol, 1 eq.) was alkylated with 4′-bromomethyl-2-carbomethoxybiphenyl (2.70 g, 8.8 mmol, 1 eq.) by the procedure described in Example 1, Part A. Obtained 3.87 g of a yellow oil which was suitable for further transformation. NMR (DMSO-d6): delta 7.84-7.22 (m, 4H); 7.22 (d, 2H, J=9Hz); 7.13 (d, 2H, J=9Hz); 5.50 (s, 2H); 3.77 (s, 3H); 3.75 (s, 3H); 3.55 (s, 3H); 2.67 (t, 2H, J=7Hz); 1.67 (t of q, 2H, J=7,7Hz); 0.88 (t, 3H, J=7Hz).
Statistics shows that 2-Propyl-1H-imidazole-4,5-dicarboxylic acid dimethyl ester is playing an increasingly important role. we look forward to future research findings about 124750-59-0.
Reference:
Patent; E. I. Du Pont de Nemours and Company; US5128355; (1992); A;,
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