Discovery of 4-Iodo-1-trityl-1H-imidazole

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4-Iodo-1-trityl-1H-imidazole, and friends who are interested can also refer to it.

96797-15-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual

A 2 M isopropylmagnesium chloride solution in THF (8.60 mL, 17.2 mmol) was added dropwise to a solution of 4-iodo-1-trityl-imidazole (5.00 g, 11.5 mmol) in anhydrous THF (55 mL) at 0 C under nitrogen. The resulting mixture was stirred at 0 C for 10 minute

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4-Iodo-1-trityl-1H-imidazole, and friends who are interested can also refer to it.

Reference:
Patent; REDX PHARMA PLC; ARMER, Richard; BINGHAM, Matilda; PESNOT, Thomas; (84 pag.)WO2016/59412; (2016); A1;,