496-46-8, Adding some certain compound to certain chemical reactions, such as: 496-46-8, name is Tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 496-46-8.
14.2 g (100 mmol) of glycoluril,16.0 g (400 mmol) of sodium hydroxide and 140 mL of dimethylsulfoxide were mixed,After heating and stirring at 40 C. for 1 hour, And 34.4 g (400 mmol) of allyl chloride were added dropwise at the same temperature over 20 minutes, and the mixture was heated and stirred at 40 C. for 2 hours to complete the reaction.The resulting reaction mixture was evaporated to dryness under reduced pressure, and the obtained dry solid was separated and extracted with 400 mL of ethyl acetate and 400 mL of water, and the ethyl acetate layer was washed with 100 mL of water, then with 100 mL of saturated brine, Dried over sodium sulfate, and ethyl acetate was distilled off under reduced pressure to obtain 27.4 g of 1,3,4,6-tetraallyl glycoluril as a colorless oil, yield 90%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 496-46-8.
Reference:
Patent; Shikoku Chemicals Co., Ltd.; Takeda, Takuma; Kashihara, Takashi; Kumano, Noboru; Mizobe, Noboru; (59 pag.)JP2015/59101; (2015); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem