Application of 1,7′-Dimethyl-2′-propyl-1H,1’H-2,5′-bibenzo[d]imidazole

According to the analysis of related databases, 152628-02-9, the application of this compound in the production field has become more and more popular.

152628-02-9, Adding a certain compound to certain chemical reactions, such as: 152628-02-9, name is 1,7′-Dimethyl-2′-propyl-1H,1’H-2,5′-bibenzo[d]imidazole, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 152628-02-9.

Example 3 Preparation of f4′ – [2-n-propyl-4-methyl-6-(1-methyl benzimidazol-2-vl) benzimidazol -1-vl methvll biphenvl-2-carboxvlic acidl 50 gm of [1 H – Benzimidazole-2-n – propyl-4-methyl-6-(1′-methyl benzimidazole-2′- yl) ] was added to 200 ml dimethyl sulfoxide and 50 gm of sodium hydroxide. To this was added 60 gm of methyl-4- (bromomethyl) biphenyl-2-carboxylate at ambient temperature. The contents were stirred for 2 hours at 25-30 C and then heated to 40-50 and maintained for 2 hours. About 500 ml water was added to the reaction mixture and acidified with acetic acid to pH 4.2, extract4ed twice with 250 ml of dichloromethane and the combined extracts were concentrated and isolated by filtration after addition of 300 ml acetone, dried under reduced pressure at 50-60 C to give 75.0 gm (80%) of the title compound.

According to the analysis of related databases, 152628-02-9, the application of this compound in the production field has become more and more popular.

Reference:
Patent; CIPLA LIMITED; TURNER, Craig, Robert; WO2005/108375; (2005); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem