15813-09-9, Adding a certain compound to certain chemical reactions, such as: 15813-09-9, name is 4,5-Diiodo-1H-imidazole, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 15813-09-9.
Preparation 71 4-iodo-1H-imidazole To a solution of 4,5-diiodo-1H-imidazole (Preparation 70, 7.7 g, 24 mmol) in ethanol (80 ml) and water (20 ml) was added solid sodium sulfite heptahydrate (20 g, 79 mmol). The reaction mixture was heated at reflux for 16 h, cooled, and the solid by-products were removed by filtration. The filtrate was then concentrated in vacuo and the resultant solid was dnred by suction. The crude residue was recrvstallised from dichloromethane to give the title compound as a white solid (4.6 g, 64%). NMR (CDCl3, selected data for the free base: 7.0 (s 1H), 7.5 (s, 1H). MS (TSP): M/Z (MH+): 195.2; C3H3129IN2+H requires 194.9.
According to the analysis of related databases, 15813-09-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Pfizer INC; US6313312; (2001); B1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem