7098-07-9, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 7098-07-9, name is 1-Ethyl-1H-imidazole, A new synthetic method of this compound is introduced below.
Dichloromethane (1.699 g, 20 mmol)And 1-ethylimidazole (5.768 g, 60 mmol) was added to the reaction flask.Then, after reacting in a closed vessel at 75 C for 24 h, after the reaction is completed, it is cooled to room temperature, and the solvent is evaporated to dryness.Dissolved in a small amount of methanol, added to a large amount of tetrahydrofuran and stirred at room temperature for 2 h.There are a lot of white solids generated,Filtered, washed with tetrahydrofuran, dried in vacuo,A white solid was obtained to give the title compound 2.48 g, yield 44.8%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Sun Yat-sen University; Mao Zongwan; Li Yi; Tan Caiping; Huang Huazhen; Ji Liangnian; (12 pag.)CN104230998; (2016); B;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem