The chemical industry reduces the impact on the environment during synthesis 288-32-4, name is 1H-Imidazole, I believe this compound will play a more active role in future production and life. 288-32-4
Compound XIII (880g, 12.9mol, 1.0eq.) In the autoclave 50L, 12L DMF were dissolved, cooled To below 0 ¡ãC, triethylamine (1308g, 12.9mol, 1.0eq. ) The reaction was kept 30min, 0 ¡ã C solution of the following threePhenyl chloride (3605.0g, 12.9mol, 1.0eq. ) In DMF (16L), drops Bi, 15 ¡ã C overnight with stirring 16 h. Thereaction mixture was poured into water, large amount of solid precipitated, suction filtered, the filter cake washedwith water, drained, dried to obtain compound XIV-1 White The solid 3835.1g, Yield: 95.6percent.
The chemical industry reduces the impact on the environment during synthesis 288-32-4. I believe this compound will play a more active role in future production and life.
Reference:
Patent; PharmaBlock Sciences (Nanjing), Inc.; MAO, JUN; ZHU, JINGWEI; SHU, QINGNING; ZHAO, SHUHAI; YANG, MINMIN; WU, XIHAN; (14 pag.)CN104086553; (2016); B;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem