Continuously updated synthesis method about 693-98-1

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 693-98-1, other downstream synthetic routes, hurry up and to see.

A common compound: 693-98-1, name is 2-Methyl-1H-imidazole, belongs to imidazoles-derivatives compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below. 693-98-1

General procedure: alpha,beta-unsaturated compound (4.8 mmol) was added dropwise to a well stirred mixture of N-heterocycle substrate (4.0 mmol) in [n-butyl urotropinium]OH (0.108 g, 0.25 mmol) and the reaction mixture was stirred for required time until completion of reaction (TLC). The product was then directly distilled out from the reaction mixture to provide pure Michael adducts (3a-3f and 4a-4f) in high yields.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 693-98-1, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Kumar, Sitanshu; Kaur, Amanpreet; Singh, Vasundhara; Synthetic Communications; vol. 49; 2; (2019); p. 193 – 201;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem