In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 3034-50-2 as follows. 3034-50-2
18-1-1 1-Trityl- 1 H-imidazole-4-carbaldehyde; To a solution containing 1 g (10.4 mmol) of 1 H-imidazole-4-carbaldehyde and 3.18 g (1 1 .4 mmol) of trityl chloride suspended in 28 ml. of acetonitrile are added dropwise 2.5 ml. (17.7 mmol) of triethylamine. After stirring for 2 hours at room temperature, 30 ml_ of water are added and the crude reaction product is filtered. 3.2 g in the form of a beige-coloured powder are obtained and used in the following step without further purification.
According to the analysis of related databases, 3034-50-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GALDERMA RESEARCH & DEVELOPMENT; BOUIX-PETER, Claire; SUZUKI, Itaru; PELISSON, Isabelle; COLLETTE, Pascal; TABET, Samuel; LAFITTE, Guillaume; WO2010/52255; (2010); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem