60-56-0, name is 1-Methyl-1H-imidazole-2(3H)-thione, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 60-56-0
2-chlorosulfonyl-1-methylimidazole Bleach (12% w/w aq, 110 ml) was cautiously added dropwise to a solution of 2-mercapto-1-methylimidazole (2.0 g) in conc. H2SO4 (50 ml) cooled to 0 C. After stirring 30 minutes at 0 C. the mixture was diluted with H2O (30 ml) and dichloromethane (30 ml). The aqueous layer was re-extracted with dichloromethane and the combined organic layers dried (MgSO4) and evaporated to give the product as an oil (730 mg).
Statistics shows that 60-56-0 is playing an increasingly important role. we look forward to future research findings about 1-Methyl-1H-imidazole-2(3H)-thione.
Reference:
Patent; Lewis, Huw David; Harrison, Timothy; Shearman, Mark Steven; US2009/215775; (2009); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem